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Drug Name | Fingolimod |
Trade Name | Gilenya |
Synonyms | FTY720 |
Drug Descriptions |
Gilenya (fingolimod) is a sphingosine 1-phosphate receptor modulator that activates PP2A, which may result in restoration of tumor suppressor activity thereby leading to apoptosis and inhibition of cell proliferation (PMID: 24448818). Gilenya (fingolimod) is FDA approved for multiple sclerosis (FDA.gov). |
DrugClasses | PP2A Activator 7 |
CAS Registry Number | 162359-55-9 |
NCIT ID | C74202 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Daunorubicin + Fingolimod | Daunorubicin Fingolimod | 1 | 0 |
Fingolimod | Fingolimod | 2 | 1 |
Fingolimod + Gemcitabine | Fingolimod Gemcitabine | 0 | 0 |
Fingolimod + Sorafenib | Fingolimod Sorafenib | 0 | 0 |