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Drug Name | Amuvatinib |
Trade Name | |
Synonyms | MP470|HPK56|MP-470 |
Drug Descriptions |
Amuvatinib (MP470) is a multi-kinase inhibitor, with activity against KIT, MET, AXL, RET, FLT3, and PDGFR-alpha, that also inhibits Rad51 induction, which may enhance the efficacy of chemotherapeutic agents (PMID: 17325667, PMID: 21903282, PMID: 20563581, PMID: 24849582). |
DrugClasses | AXL Inhibitor 30 FLT3 Inhibitor 69 KIT Inhibitor 57 MET Inhibitor 59 PDGFR-alpha Inhibitor 9 RET Inhibitor 53 |
CAS Registry Number | 850879-09-3 |
NCIT ID | C71750 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Amuvatinib | Amuvatinib | 0 | 0 |
Amuvatinib + Carboplatin + Paclitaxel | Amuvatinib Carboplatin Paclitaxel | 0 | 0 |