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Drug Name | ENMD-2076 |
Trade Name | |
Synonyms | ENMD 2076|ENMD2076 |
Drug Descriptions |
ENMD-2076 has selective inhibitory activity against Aurora kinase A and FLT3, with reduced potency against RET, KDR (VEGFR2), FGFR1, and FGFR2, preventing angiogenesis and decreasing cell proliferation (PMID: 21177375, PMID: 22921155, PMID: 32154962). |
DrugClasses | Aurka Inhibitors 27 FGFR1 Inhibitor 28 FGFR2 Inhibitor 23 FLT3 Inhibitor 69 RET Inhibitor 53 VEGFR2 Inhibitor 37 |
CAS Registry Number | 1453868-32-0 |
NCIT ID | C78190 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ENMD-2076 | ENMD-2076 | 2 | 4 |