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Drug Name | JNJ 38877605 |
Trade Name | |
Synonyms | JNJ38877605|JNJ-38877605 |
Drug Descriptions |
JNJ 38877605 binds to MET and prevents its activation, resulting in decreased downstream signaling and potentially resulting in increased cell death of MET-overexpressing tumor cells (PMID: 31881189, PMID: 30284817). |
DrugClasses | MET Inhibitor 59 |
CAS Registry Number | 943540-75-8 |
NCIT ID | C77893 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cetuximab + JNJ 38877605 | Cetuximab JNJ 38877605 | 0 | 0 |
JNJ 38877605 | JNJ 38877605 | 0 | 0 |
JNJ 38877605 + Olaparib | JNJ 38877605 Olaparib | 0 | 0 |
JNJ 38877605 + Panitumumab | JNJ 38877605 Panitumumab | 0 | 0 |