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Drug Name | KX2-391 |
Trade Name | |
Synonyms | KX-01|Tirbanibulin |
Drug Descriptions |
Tirbanibulin (KX2-391) is a peptidomimetic inhibitor of Src and pretubulin, with additional activity against FLT3, potentially resulting in decreased tumor growth and metastasis (PMID: 22784709, PMID: 31628188, PMID: 34217323). |
DrugClasses | FLT3 Inhibitor 69 SRC Inhibitor 31 |
CAS Registry Number | 897016-82-9 |
NCIT ID | C74077 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
KX2-391 | KX2-391 | 10 | 2 |
KX2-391 + Oxaliplatin | KX2-391 Oxaliplatin | 2 | 0 |
KX2-391 + Paclitaxel | KX2-391 Paclitaxel | 0 | 0 |
KX2-391 + Tamoxifen | KX2-391 Tamoxifen | 0 | 0 |