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Drug Name Masitinib
Trade Name
Synonyms AB1010
Drug Descriptions

Masitinib (AB1010) inhibits several receptor tyrosine kinases including c-KIT, PDGFR, and LYN, which may result in inhibition of cell proliferation (PMID: 19789626, PMID: 29638149).

DrugClasses KIT Inhibitor 57 LYN Inhibitor 4 PDGFR Inhibitor (Pan) 30
CAS Registry Number 790299-79-5
NCIT ID C79910

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Docetaxel + Masitinib + Prednisone Docetaxel Masitinib Prednisone 0 1
Gemcitabine + Masitinib Gemcitabine Masitinib 0 0
Masitinib Masitinib 0 5


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