PX-866
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| Drug Name | PX-866 |
| Trade Name | |
| Synonyms | Sonolisib|PX866 |
| Drug Descriptions |
Sonolisib (PX-866) is a PI3K inhibitor, which inhibits the activation of the PI3K/Akt signaling pathway, thereby inhibiting cancer cell motility and growth (PMID: 17766839). |
| DrugClasses | PI3K Inhibitor (Pan) 42 |
| CAS Registry Number | 502632-66-8 |
| NCIT ID | C78848 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abiraterone + PX-866 | Abiraterone PX-866 | 0 | 0 |
| PX-866 | PX-866 | 3 | 0 |
| PX-866 + Sorafenib | PX-866 Sorafenib | 0 | 0 |
| PX-866 + Vemurafenib | PX-866 Vemurafenib | 1 | 0 |
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