RO4929097
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| Drug Name | RO4929097 |
| Trade Name | |
| Synonyms | RG-4733 |
| Drug Descriptions |
RO4929097 (RG-4733) is a gamma secretase inhibitor, which blocks Notch cleavage and activation, and may inhibit angiogenesis and tumor growth (PMID: 19773430, PMID: 31953695). |
| DrugClasses | Gamma secretase inhibitor 13 |
| CAS Registry Number | 847925-91-1 |
| NCIT ID | C88333 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Paclitaxel + RO4929097 | Carboplatin Paclitaxel RO4929097 | 0 | 0 |
| Paclitaxel + RO4929097 | Paclitaxel RO4929097 | 0 | 0 |
| Radiotherapy + RO4929097 + Temozolomide | RO4929097 Radiotherapy Temozolomide | 0 | 0 |
| RO4929097 | RO4929097 | 0 | 1 |
| RO4929097 + Vismodegib | RO4929097 Vismodegib | 0 | 1 |
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