Tesevatinib
Drug Detail
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| Drug Name | Tesevatinib |
| Trade Name | |
| Synonyms | KD019|XL647|EXEL 7647|KD 019 |
| Drug Descriptions |
Tesevatinib (XL647) is an inhibitor of multiple receptor tyrosine kinases, including ERBB2 (HER2), EGFR, VEGFR2 and VEGFR3, and EphB4, potentially resulting in decreased tumor growth and angiogenesis (PMID: 17575237, PMID: 30030583). |
| DrugClasses | EGFR Inhibitor (Pan) 63 EPHB4 Inhibitor 6 HER2 Inhibitor 44 VEGFR2 Inhibitor 37 VEGFR3 Inhibitor 6 |
| CAS Registry Number | 781613-23-8 |
| NCIT ID | C62496 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Tesevatinib | Tesevatinib | 0 | 2 |
| Tesevatinib + Trastuzumab | Tesevatinib Trastuzumab | 0 | 1 |
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