Brontictuzumab
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| Drug Name | Brontictuzumab |
| Trade Name | |
| Synonyms | OMP-52M51 |
| Drug Descriptions |
Brontictuzumab (OMP-52M51) is a monoclonal antibody that binds Notch1 and prevents ligand interaction and pathway activation, which may inhibit angiogenesis and tumor growth (PMID: 23774673, PMID: 31616059, PMID: 29726923). |
| DrugClasses | NOTCH1 Antibody 2 |
| CAS Registry Number | 1447814-75-6 |
| NCIT ID | C103274 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Brontictuzumab | Brontictuzumab | 0 | 2 |
| Brontictuzumab + Trifluridine | Brontictuzumab Trifluridine | 0 | 1 |
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