Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | AMG 900 |
Trade Name | |
Synonyms | AMG900|AMG-900 |
Drug Descriptions |
AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may result in inhibition of cellular division and proliferation in tumor cells that overexpress these kinases (PMID: 25367255, PMID: 32138169). |
DrugClasses | AURK Inhibitor (Pan) 12 |
CAS Registry Number | 945595-80-2 |
NCIT ID | C82349 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AMG 900 | AMG 900 | 1 | 1 |
AMG 900 + Ixabepilone | AMG 900 Ixabepilone | 0 | 0 |