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Drug Name | Brivanib |
Trade Name | |
Synonyms | BMS-540215|BMS540215 |
Drug Descriptions |
Brivanib (BMS-540215) selectively binds and inhibits KDR (VEGFR2), while demonstrating moderate activity against VEGFR1 and FGFR1, which inhibits tumor angiogenesis, tumor cell growth, and induces tumor regression (PMID: 18829493, PMID: 16570908, PMID: 32434345, PMID: 31522033). |
DrugClasses | FGFR1 Inhibitor 28 VEGFR1 Inhibitor 6 VEGFR2 Inhibitor 37 |
CAS Registry Number | 649735-46-6 |
NCIT ID | C67040 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Brivanib | Brivanib | 12 | 0 |