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| Drug Name | Carboxyamidotriazole Orotate |
| Trade Name | |
| Synonyms | CTO |
| Drug Descriptions |
Carboxyamidotriazole orotate binds to and inhibits non-voltage-operated calcium channels and inhibits PI3 activity and vascular endothelial growth factor (VEGF) signaling (PMID: 29731337). |
| DrugClasses | |
| CAS Registry Number | 187739-60-2 |
| NCIT ID | C91090 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bevacizumab + Carboxyamidotriazole Orotate | Bevacizumab Carboxyamidotriazole Orotate | 0 | 0 |
| Carboxyamidotriazole Orotate | Carboxyamidotriazole Orotate | 2 | 3 |
| Carboxyamidotriazole Orotate + Paclitaxel | Carboxyamidotriazole Orotate Paclitaxel | 0 | 0 |
| Carboxyamidotriazole Orotate + Temozolomide | Carboxyamidotriazole Orotate Temozolomide | 0 | 1 |