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Drug Name | Carboxyamidotriazole Orotate |
Trade Name | |
Synonyms | CTO |
Drug Descriptions |
Carboxyamidotriazole orotate binds to and inhibits non-voltage-operated calcium channels and inhibits PI3 activity and vascular endothelial growth factor (VEGF) signaling (PMID: 29731337). |
DrugClasses | |
CAS Registry Number | 187739-60-2 |
NCIT ID | C91090 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + Carboxyamidotriazole Orotate | Bevacizumab Carboxyamidotriazole Orotate | 0 | 0 |
Carboxyamidotriazole Orotate | Carboxyamidotriazole Orotate | 2 | 3 |
Carboxyamidotriazole Orotate + Paclitaxel | Carboxyamidotriazole Orotate Paclitaxel | 0 | 0 |
Carboxyamidotriazole Orotate + Temozolomide | Carboxyamidotriazole Orotate Temozolomide | 0 | 1 |