Zoligratinib
Drug Detail
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| Drug Name | Zoligratinib |
| Trade Name | |
| Synonyms | CH5183284|FF284|debiopharm 1347|Debio 1347|Debio1347|Debio-1347|FF284 |
| Drug Descriptions |
Zoligratinib inhibits FGFR-1, -2, and -3, resulting in decreased downstream signaling, and potentially leading to reduced tumor cell proliferation and angiogenesis, and increased cell death in FGFR-overexpressing tumor cells (PMID: 30745300). |
| DrugClasses | FGFR1 Inhibitor 28 FGFR2 Inhibitor 24 FGFR3 Inhibitor 21 |
| CAS Registry Number | 1265229-25-1 |
| NCIT ID | C174762 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Fulvestrant + Zoligratinib | Fulvestrant Zoligratinib | 0 | 1 |
| Zoligratinib | Zoligratinib | 58 | 2 |
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