Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Zoligratinib |
Trade Name | |
Synonyms | CH5183284|FF284|debiopharm 1347|Debio 1347|Debio1347|Debio-1347|FF284 |
Drug Descriptions |
Zoligratinib inhibits FGFR-1, -2, and -3, resulting in decreased downstream signaling, and potentially leading to reduced tumor cell proliferation and angiogenesis, and increased cell death in FGFR-overexpressing tumor cells (PMID: 30745300). |
DrugClasses | FGFR1 Inhibitor 28 FGFR2 Inhibitor 23 FGFR3 Inhibitor 19 |
CAS Registry Number | 1265229-25-1 |
NCIT ID | C174762 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Fulvestrant + Zoligratinib | Fulvestrant Zoligratinib | 0 | 1 |
Zoligratinib | Zoligratinib | 58 | 2 |