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Drug Name | Serabelisib |
Trade Name | |
Synonyms | INK1117|TAK-117|MLN-1117|MLN1117 |
Drug Descriptions |
Serabelisib (MLN1117) selectively inhibits PI3K alpha kinase, including mutations of PIK3CA, and therefore, targets the PI3K/Akt/mTOR pathway with potentially less toxicity than pan-PI3K inhibitors (PMID: 28490463, PMID: 30168905). |
DrugClasses | PIK3CA inhibitor 24 |
CAS Registry Number | 1268454-23-4 |
NCIT ID | C98844 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Mivavotinib + Serabelisib | Mivavotinib Serabelisib | 0 | 0 |
Nab-paclitaxel + Serabelisib | Nab-paclitaxel Serabelisib | 0 | 1 |
Paclitaxel + Sapanisertib + Serabelisib | Paclitaxel Sapanisertib Serabelisib | 0 | 1 |
Sapanisertib + Serabelisib | Sapanisertib Serabelisib | 0 | 4 |
Serabelisib | Serabelisib | 4 | 3 |