Rebastinib
Drug Detail
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| Drug Name | Rebastinib |
| Trade Name | |
| Synonyms | DCC-2036 |
| Drug Descriptions |
Rebastinib (DCC-2036) inhibits BCR-ABL1 and ABL1 mutations including T315I, and has some activity against TIE-2, FLT3, and VEGFR2, potentially resulting in decreased tumor cell growth (PMID: 21481795, PMID: 31763674). |
| DrugClasses | BCR-ABL Inhibitor 32 FLT3 Inhibitor 69 TIE2 Inhibitor 3 VEGFR2 Inhibitor 37 |
| CAS Registry Number | 1020172-07-9 |
| NCIT ID | C152162 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Rebastinib | Carboplatin Rebastinib | 0 | 1 |
| Eribulin + Rebastinib | Eribulin Rebastinib | 0 | 1 |
| Paclitaxel + Rebastinib | Paclitaxel Rebastinib | 0 | 2 |
| Rebastinib | Rebastinib | 1 | 0 |
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