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| Drug Name | Varlitinib |
| Trade Name | |
| Synonyms | ARRY-334543|ARRY-543 |
| Drug Descriptions |
Varlitinib is a selective inhibitor of EGFR and ERBB2 (HER2), which inhibits downstream signaling, potentially resulting in decreased tumor cell proliferation and increased cell death (PMID: 30658422). |
| DrugClasses | EGFR Inhibitor (Pan) 65 HER2 Inhibitor 43 |
| CAS Registry Number | 845272-21-1 |
| NCIT ID | C62530 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Capecitabine + Varlitinib | Capecitabine Varlitinib | 0 | 1 |
| Trastuzumab + Varlitinib | Trastuzumab Varlitinib | 0 | 0 |
| Varlitinib | Varlitinib | 0 | 0 |
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