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Drug Name | Varlitinib |
Trade Name | |
Synonyms | ARRY-334543|ARRY-543 |
Drug Descriptions |
Varlitinib is a selective inhibitor of EGFR and ERBB2 (HER2), which inhibits downstream signaling, potentially resulting in decreased tumor cell proliferation and increased cell death (PMID: 30658422). |
DrugClasses | EGFR Inhibitor (Pan) 62 HER2 Inhibitor 42 |
CAS Registry Number | 845272-21-1 |
NCIT ID | C62530 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Capecitabine + Varlitinib | Capecitabine Varlitinib | 0 | 1 |
Trastuzumab + Varlitinib | Trastuzumab Varlitinib | 0 | 0 |
Varlitinib | Varlitinib | 0 | 0 |