REGN1400
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| Drug Name | REGN1400 |
| Trade Name | |
| Synonyms | REGN-1400|REGN 1400 |
| Drug Descriptions |
REGN1400 is a monoclonal antibody, which binds to epidermal growth factor receptor B3 (Her3), preventing neuregulin 1 ligand binding, thereby inhibiting PI3K/Akt signaling and hence cellular proliferation (PMID: 24634416). |
| DrugClasses | HER3 (ERBB3) Antibody 28 |
| CAS Registry Number | NA |
| NCIT ID | C103859 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cetuximab + REGN1400 | Cetuximab REGN1400 | 0 | 1 |
| Erlotinib + REGN1400 | Erlotinib REGN1400 | 0 | 1 |
| REGN1400 | REGN1400 | 0 | 1 |
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