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Drug Name | Naquotinib |
Trade Name | |
Synonyms | ASP8273 |
Drug Descriptions |
Naquotinib (ASP8273) is a third-generation EGFR inhibitor that binds mutant forms of EGFR, including T790M, and also inhibits AXL, thus may lead to growth inhibition in tumor cells (PMID: 29467275, PMID: 31092564). |
DrugClasses | AXL Inhibitor 30 EGFR Inhibitor 3rd gen 26 |
CAS Registry Number | 1448232-80-1 |
NCIT ID | C115110 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
JBJ-04-125-02 + Naquotinib | JBJ-04-125-02 Naquotinib | 0 | 0 |
Naquotinib | Naquotinib | 0 | 5 |