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Drug Name | PRI-724 |
Trade Name | |
Synonyms | PRI 724|PRI724 |
Drug Descriptions |
PRI-724 is a Wnt signaling pathway inhibitor which antagonistically inhibits the recruiting of beta-catenin with its coactivator CBP, thereby inhibiting tumor growth (PMID: 31550723). |
DrugClasses | CTNNB1 Inhibitor 27 |
CAS Registry Number | 1198780-38-9 |
NCIT ID | C95894 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cytarabine + PRI-724 | Cytarabine PRI-724 | 0 | 1 |
Dasatinib + PRI-724 | Dasatinib PRI-724 | 0 | 1 |
Gemcitabine + PRI-724 | Gemcitabine PRI-724 | 0 | 1 |
PRI-724 | PRI-724 | 0 | 3 |