Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | K252a |
Trade Name | |
Synonyms | K252-a|K252 a|K-252a |
Drug Descriptions |
K-252a is an ATP-competitive inhibitor of cyclic nucleotide-dependent protein kinases and protein kinase C, and also has inhibitory activity against TRKs and MET, potentially resulting in decreased downstream signaling and reduced tumor cell proliferation (PMID: 3028414, PMID: 12118367). |
DrugClasses | MET Inhibitor 59 PKC Inhibitor (Pan) 11 Trk Receptor Inhibitor (Pan) 32 |
CAS Registry Number | 99533-80-9 |
NCIT ID | C1382 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Afatinib + K252a | Afatinib K252a | 0 | 0 |
K252a | K252a | 0 | 0 |