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Drug Name K252a
Trade Name
Synonyms K252-a|K252 a|K-252a
Drug Descriptions

K-252a is an ATP-competitive inhibitor of cyclic nucleotide-dependent protein kinases and protein kinase C, and also has inhibitory activity against TRKs and MET, potentially resulting in decreased downstream signaling and reduced tumor cell proliferation (PMID: 3028414, PMID: 12118367).

DrugClasses MET Inhibitor 59 PKC Inhibitor (Pan) 11 Trk Receptor Inhibitor (Pan) 32
CAS Registry Number 99533-80-9
NCIT ID C1382

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + K252a Afatinib K252a 0 0
K252a K252a 0 0


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