K252a
Drug Detail
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| Drug Name | K252a |
| Trade Name | |
| Synonyms | K252-a|K252 a|K-252a |
| Drug Descriptions |
K-252a is an ATP-competitive inhibitor of cyclic nucleotide-dependent protein kinases and protein kinase C, and also has inhibitory activity against TRKs and MET, potentially resulting in decreased downstream signaling and reduced tumor cell proliferation (PMID: 3028414, PMID: 12118367). |
| DrugClasses | MET Inhibitor 59 PKC Inhibitor (Pan) 11 Trk Receptor Inhibitor (Pan) 33 |
| CAS Registry Number | 99533-80-9 |
| NCIT ID | C1382 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Afatinib + K252a | Afatinib K252a | 0 | 0 |
| K252a | K252a | 0 | 0 |
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