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Drug Name | Rasdegafusp alfa |
Trade Name | |
Synonyms | CDX-1401|DEC-205/NY-ESO-1 fusion protein vaccine |
Drug Descriptions |
Rasdegafusp alfa (CDX-1401) is a DEC-205/NY-ESO-1 fusion protein vaccine that consists of a monoclonal antibody directed against the dendritic cell receptor DEC-205 linked to the tumor-associated antigen DEC-205/NY-ESO-1 fusion protein, which may boost the immune system to attack cancer cells expressing DEC-205/NY-ESO-1 fusion protein (PMID: 24739759). |
DrugClasses | |
CAS Registry Number | 1587257-96-2 |
NCIT ID | C170362 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Guadecitabine + Rasdegafusp alfa | Atezolizumab Guadecitabine Rasdegafusp alfa | 0 | 1 |
Atezolizumab + Rasdegafusp alfa | Atezolizumab Rasdegafusp alfa | 0 | 1 |
Decitabine + Nivolumab + Poly ICLC + Rasdegafusp alfa | Decitabine Nivolumab Poly ICLC Rasdegafusp alfa | 0 | 1 |
Decitabine + Rasdegafusp alfa | Decitabine Rasdegafusp alfa | 0 | 1 |
Rasdegafusp alfa | Rasdegafusp alfa | 0 | 4 |