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Drug Name | DNIB0600A |
Trade Name | |
Synonyms | Lifastuzumab vedotin|RG-7599 |
Drug Descriptions |
DNIB0600A (Lifastuzumab vedotin) is an antibody-drug conjugate consists of an antibody targeting SLC34A2 and monomethyl auristatin E, which may lead to disruption of the microtubule network in SLC34A2-expressing cancer cells, thereby potentially inhibiting cell proliferation (PMID: 29401246, PMID: 32534811, PMID: 31540980). |
DrugClasses | |
CAS Registry Number | 1401812-88-1 |
NCIT ID | C116747 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + Carboplatin + DNIB0600A | Bevacizumab Carboplatin DNIB0600A | 0 | 1 |
Carboplatin + DNIB0600A | Carboplatin DNIB0600A | 0 | 1 |
DNIB0600A | DNIB0600A | 0 | 1 |