Galeterone
Drug Detail
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| Drug Name | Galeterone |
| Trade Name | |
| Synonyms | TOK-001|VN-124 |
| Drug Descriptions |
Galeterone functions both as an inhibitor of CYP17A1 and anti-androgen, as it binds the androgen receptor, acting as an competitive antagonist and also preventing Ar protein binding to chromatin and enhancing degradation of mutant Ar protein (PMID: 24874833, PMID: 31653008). |
| DrugClasses | Hormone - Anti-androgens 57 |
| CAS Registry Number | 851983-85-2 |
| NCIT ID | C84866 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Galeterone | Galeterone | 0 | 3 |
| Galeterone + Gemcitabine | Galeterone Gemcitabine | 0 | 1 |
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