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Drug Name | Fostamatinib |
Trade Name | Tavalisse |
Synonyms | R788|R935788 |
Drug Descriptions |
Fostamatinib (R788) binds and inhibits Syk kinase thus interfering with mast cell, macrophage, and B-cell activation as well as downstream events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis (NCI Drug Dictionary). |
DrugClasses | SYK Inhibitor 15 |
CAS Registry Number | 901119-35-5 |
NCIT ID | C95222 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Fostamatinib | Fostamatinib | 1 | 2 |
Fostamatinib + Paclitaxel | Fostamatinib Paclitaxel | 0 | 1 |
Fostamatinib + Silmitasertib | Fostamatinib Silmitasertib | 0 | 0 |