AZD3463
Drug Detail
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| Drug Name | AZD3463 |
| Trade Name | |
| Synonyms | AZD-3463|AZD 3463 |
| Drug Descriptions |
AZD3463 inhibits IGF1R and ALK, including wild-type and mutant ALK, and has additional activity against ROS1 fusions, which decreases downstream signaling resulting in reduced tumor cell growth (PMID: 26786851, PMID: 26372962, PMID: 32698744, PMID: 32355780). |
| DrugClasses | ALK Inhibitor 33 IGF-1R Inhibitor 17 ROS1 Inhibitor 23 |
| CAS Registry Number | 1356962-20-3 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AZD3463 | AZD3463 | 7 | 0 |
| AZD3463 + Doxorubicin | AZD3463 Doxorubicin | 1 | 0 |
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