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Drug Name | AZD3463 |
Trade Name | |
Synonyms | AZD-3463|AZD 3463 |
Drug Descriptions |
AZD3463 inhibits IGF1R and ALK, including wild-type and mutant ALK, and has additional activity against ROS1 fusions, which decreases downstream signaling resulting in reduced tumor cell growth (PMID: 26786851, PMID: 26372962, PMID: 32698744, PMID: 32355780). |
DrugClasses | ALK Inhibitor 33 IGF-1R Inhibitor 17 ROS1 Inhibitor 22 |
CAS Registry Number | 1356962-20-3 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD3463 | AZD3463 | 7 | 0 |
AZD3463 + Doxorubicin | AZD3463 Doxorubicin | 1 | 0 |