Cyclopamine
Drug Detail
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| Drug Name | Cyclopamine |
| Trade Name | |
| Synonyms | 11-Deoxyjervine |
| Drug Descriptions |
Cyclopamine (11-Deoxyjervine) is a plant-derived alkaloid that inhibits the Hedgehog signaling pathway, resulting in growth inhibition in cells with activated SMO or inactivated PTCH (PMID: 10984056, PMID: 32622951). |
| DrugClasses | SMO Inhibitor 16 |
| CAS Registry Number | 4449-51-8 |
| NCIT ID | C63945 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cyclopamine | Cyclopamine | 0 | 0 |
| Cyclopamine + Posaconazole | Cyclopamine Posaconazole | 0 | 0 |
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