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Drug Name | Cyclopamine |
Trade Name | |
Synonyms | 11-Deoxyjervine |
Drug Descriptions |
Cyclopamine (11-Deoxyjervine) is a plant-derived alkaloid that inhibits the Hedgehog signaling pathway, resulting in growth inhibition in cells with activated SMO or inactivated PTCH (PMID: 10984056, PMID: 32622951). |
DrugClasses | SMO Inhibitor 16 |
CAS Registry Number | 4449-51-8 |
NCIT ID | C63945 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclopamine | Cyclopamine | 0 | 0 |
Cyclopamine + Posaconazole | Cyclopamine Posaconazole | 0 | 0 |