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Drug Name | GANT61 |
Trade Name | |
Synonyms | GANT-61 |
Drug Descriptions |
GANT61 is a small molecule inhibitor of hedgehog signaling that acts on GLI1 and GLI2 to block transcription and has demonstrated antitumor activity in xenograft models (PMID: 17494766, PMID: 32677544, PMID: 32504326). |
DrugClasses | GLI1/2 inhibitor 6 |
CAS Registry Number | 500579-04-4 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Doxorubicin + GANT61 | Doxorubicin GANT61 | 0 | 0 |
GANT61 | GANT61 | 0 | 0 |
GANT61 + Olaparib | GANT61 Olaparib | 0 | 0 |
GANT61 + Vincristine Sulfate | GANT61 Vincristine Sulfate | 0 | 0 |