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Drug Name | Apatorsen |
Trade Name | |
Synonyms | OGX-427|ISIS 306053|OGX427|OGX 427|ISIS-306053|ISIS 306053 |
Drug Descriptions |
Apatorsen (OGX-427) is an antisense oligonucleotide that targets HSBP1 (HSP27), which reduces Hsbp1 expression, potentially resulting in increased tumor cell apoptosis and improved sensitivity to other anti-tumor therapies (PMID: 31420467). |
DrugClasses | Antisense Therapy 14 |
CAS Registry Number | 1002331-21-6 |
NCIT ID | C71740 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Apatorsen | Apatorsen | 0 | 3 |
Apatorsen + Carboplatin + Pemetrexed Disodium | Apatorsen Carboplatin Pemetrexed Disodium | 0 | 0 |
Apatorsen + Gemcitabine | Apatorsen Gemcitabine | 0 | 0 |