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Drug Name | Chiauranib |
Trade Name | |
Synonyms | CS2164 |
Drug Descriptions |
Chiauranib (CS2164) is a multi-kinase inhibitor that inhibits AURKB, CSF-1R, VEGFRs, KIT, and PDGFRA, resulting in decreased tumor growth and angiogenesis (PMID: 28004478, PMID: 30642372). |
DrugClasses | Aurkb Inhibitors 21 CSF1R Inhibitor 28 KIT Inhibitor 57 PDGFR-alpha Inhibitor 9 VEGFR Inhibitor (Pan) 36 |
CAS Registry Number | 1256349-48-0 |
NCIT ID | C115970 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cadonilimab + Chiauranib | Cadonilimab Chiauranib | 0 | 1 |
Chiauranib | Chiauranib | 0 | 2 |