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Drug Name | Tranylcypromine |
Trade Name | Parnate |
Synonyms | Dl-Tranylcypromine |
Drug Descriptions |
Parnate (tranylcypromine) is a monoamine oxidase inhibitor (MAOI) that also inhibits Kdm1a (Lsd1), which may lead to inhibition of stem cell growth through epigenetic regulation (PMID: 26748182). |
DrugClasses | KDM1A Inhibitor 15 |
CAS Registry Number | 155-09-9 |
NCIT ID | C61979 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cytarabine + Tranylcypromine + Tretinoin | Cytarabine Tranylcypromine Tretinoin | 0 | 1 |
Tranylcypromine | Tranylcypromine | 0 | 0 |
Tranylcypromine + Tretinoin | Tranylcypromine Tretinoin | 0 | 1 |