S-49076
Drug Detail
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| Drug Name | S-49076 |
| Trade Name | |
| Synonyms | S49076 |
| Drug Descriptions |
S-49076 is a multi-kinase inhibitor that inhibits wild-type and mutant forms of MET and FGFR1-2, as well as FGFR3, AXL, MER, and AURKB, resulting in decreased downstream signaling, and potentially resulting in decreased tumor growth (PMID: 23804704, PMID: 28624695, PMID: 28619752). |
| DrugClasses | Aurkb Inhibitors 21 AXL Inhibitor 30 FGFR1 Inhibitor 28 FGFR2 Inhibitor 24 FGFR3 Inhibitor 21 MET Inhibitor 59 |
| CAS Registry Number | 1265965-22-7 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Bevacizumab + S-49076 | Bevacizumab S-49076 | 0 | 0 |
| S-49076 | S-49076 | 2 | 0 |
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