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Drug Name | S-49076 |
Trade Name | |
Synonyms | S49076 |
Drug Descriptions |
S-49076 is a multi-kinase inhibitor that inhibits wild-type and mutant forms of MET and FGFR1-2, as well as FGFR3, AXL, MER, and AURKB, resulting in decreased downstream signaling, and potentially resulting in decreased tumor growth (PMID: 23804704, PMID: 28624695, PMID: 28619752). |
DrugClasses | Aurkb Inhibitors 21 AXL Inhibitor 30 FGFR1 Inhibitor 28 FGFR2 Inhibitor 23 FGFR3 Inhibitor 19 MET Inhibitor 59 |
CAS Registry Number | 1265965-22-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + S-49076 | Bevacizumab S-49076 | 0 | 0 |
S-49076 | S-49076 | 2 | 0 |