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Drug Name | VB-111 |
Trade Name | Ofranergene Obadenovec |
Synonyms | VB111 |
Drug Descriptions |
Ofranergene Obadenovec (VB-111) is an engineered adenovirus that expresses Fas-c specifically within endothelial cells, resulting in endothelial cell death and decreased tumor blood supply, and potentially leading to tumor cell death (PMID: 22701765) |
DrugClasses | |
CAS Registry Number | 1476737-24-2 |
NCIT ID | C71539 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Bevacizumab + VB-111 | Bevacizumab VB-111 | 0 | 2 |
Nivolumab + VB-111 | Nivolumab VB-111 | 0 | 1 |
Paclitaxel + VB-111 | Paclitaxel VB-111 | 0 | 1 |
VB-111 | VB-111 | 0 | 1 |