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Drug Name | OSU03012 |
Trade Name | |
Synonyms | AR-12|OSU-03012 |
Drug Descriptions |
OSU03012 is an inhibitor of PDPK1 and PAK1, which can indirectly inhibit beta-catenin by blocking Akt signaling resulting in apoptosis and anti-tumor activity (PMID: 20028853, PMID: 32863957). |
DrugClasses | PAK1 Inhibitor 11 PDPK1 Inhibitor 10 |
CAS Registry Number | 742112-33-0 |
NCIT ID | C88271 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
OSU03012 | OSU03012 | 0 | 0 |