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Drug Name | JW55 |
Trade Name | |
Synonyms | JW 55 |
Drug Descriptions |
JW55 selectively inhibits Wnt/beta-catenin-mediated signaling by inhibiting tankyrase1/2, thus stabilizing axin and stimulating beta-catenin degradation, which prevents cell division and decreases tumor growth (PMID: 22440753). |
DrugClasses | Tankyrase Inhibitor 11 |
CAS Registry Number | 664993-53-7 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
JW55 | JW55 | 1 | 0 |