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Drug Name | FLX925 |
Trade Name | |
Synonyms | AMG925|AMG-925|AMG 925 |
Drug Descriptions |
FLX925 (AMG925) binds to and inhibits both FMS-related tyrosine kinase 3 (FLT3) and cyclin-dependent kinases 4 and 6 (CDK4/6), resulting in cell cycle arrest and inhibition of cell proliferation (Cancer Res 2015;75(15 Suppl):Abstract nr 787, PMID: 25326874). |
DrugClasses | CDK4/6 Inhibitor 14 FLT3 Inhibitor 69 |
CAS Registry Number | 1401033-86-0 |
NCIT ID | C120209 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
FLX925 | FLX925 | 1 | 1 |