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Drug Name | Tarextumab |
Trade Name | |
Synonyms | OMP-59R5|OMP-59R5 |
Drug Descriptions |
Tarextumab (OMP-59R5) is a monoclonal antibody that binds Notch2 and Notch3 to prevent ligand interaction, which may inhibit angiogenesis and tumor growth (PMID: 25934888, PMID: 30591982). |
DrugClasses | NOTCH2 Antibody 3 NOTCH3 Antibody 2 |
CAS Registry Number | 1359940-55-8 |
NCIT ID | C95719 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Gemcitabine + Nab-paclitaxel + Tarextumab | Gemcitabine Nab-paclitaxel Tarextumab | 0 | 0 |
Gemcitabine + Tarextumab | Gemcitabine Tarextumab | 0 | 0 |
Tarextumab | Tarextumab | 0 | 2 |