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Drug Name | Milciclib |
Trade Name | |
Synonyms | PHA-848125AC|PHA-848125|PHA 848125 |
Drug Descriptions |
Milciclib (PHA-848125AC) is a TRKA inhibitor with additional activity against CDK1, CDK2, CDK4, CDK5, and CDK7, potentially resulting in decreased tumor cell growth (PMID: 22160853, PMID: 28424962). |
DrugClasses | CDK1 Inhibitor 13 CDK2 Inhibitor 31 CDK4 Inhibitor 17 CDK5 Inhibitor 8 CDK7 Inhibitor 16 TrkA Receptor Inhibitor 8 |
CAS Registry Number | 802539-81-7 |
NCIT ID | C148410 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Gemcitabine + Milciclib | Gemcitabine Milciclib | 0 | 0 |
Milciclib | Milciclib | 1 | 2 |