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Drug Name | Vonlerolizumab |
Trade Name | |
Synonyms | MOXR0916|MOXR 0916|MOXR-0916|pogalizumab|RG7888 |
Drug Descriptions |
Vonlerolizumab (MOXR0916) is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance anti-tumor immune response (PMID: 25763356). |
DrugClasses | OX40 Antibody 14 |
CAS Registry Number | 1638935-72-4 |
NCIT ID | C121376 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Vonlerolizumab | Atezolizumab Vonlerolizumab | 0 | 1 |
Vonlerolizumab | Vonlerolizumab | 0 | 2 |