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Drug Name | Seviteronel |
Trade Name | |
Synonyms | VT-464|INO-464 |
Drug Descriptions |
Seviteronel (VT-464) is a small molecule inhibitor of CYP17 17,20 lyase activity, resulting in decreased androgen production, which may inhibit growth of androgen-dependent tumors (PMID: 30012563, PMID: 25351916, PMID: 32327394). |
DrugClasses | Hormone - Anti-androgens 54 |
CAS Registry Number | 1610537-15-9 |
NCIT ID | C113652 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + Seviteronel | Abemaciclib Seviteronel | 0 | 0 |
Dexamethasone + Docetaxel + Seviteronel | Dexamethasone Docetaxel Seviteronel | 0 | 1 |
Seviteronel | Seviteronel | 0 | 1 |