Seviteronel
Drug Detail
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| Drug Name | Seviteronel |
| Trade Name | |
| Synonyms | VT-464|INO-464 |
| Drug Descriptions |
Seviteronel (VT-464) is a small molecule inhibitor of CYP17 17,20 lyase activity, resulting in decreased androgen production, which may inhibit growth of androgen-dependent tumors (PMID: 30012563, PMID: 25351916, PMID: 32327394). |
| DrugClasses | Hormone - Anti-androgens 57 |
| CAS Registry Number | 1610537-15-9 |
| NCIT ID | C113652 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abemaciclib + Seviteronel | Abemaciclib Seviteronel | 0 | 0 |
| Dexamethasone + Docetaxel + Seviteronel | Dexamethasone Docetaxel Seviteronel | 0 | 1 |
| Seviteronel | Seviteronel | 0 | 1 |
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