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Drug Name | PG545 |
Trade Name | |
Synonyms | Pixatimod |
Drug Descriptions |
Pixatimod (PG545) is a heparan sulfate mimetic capable of inhibiting both heparanase and angiogenesis, which may result in tumor growth inhibition and anti-metastatic activity (PMID: 21285983, PMID: 32274726). |
DrugClasses | |
CAS Registry Number | 1144617-49-1 |
NCIT ID | C95202 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + Nivolumab + PG545 | Cyclophosphamide Nivolumab PG545 | 0 | 1 |
Gemcitabine + PG545 | Gemcitabine PG545 | 0 | 0 |
Nivolumab + PG545 | Nivolumab PG545 | 0 | 1 |
PG545 | PG545 | 0 | 0 |