PG545
Drug Detail
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| Drug Name | PG545 |
| Trade Name | |
| Synonyms | Pixatimod |
| Drug Descriptions |
Pixatimod (PG545) is a heparan sulfate mimetic capable of inhibiting both heparanase and angiogenesis, which may result in tumor growth inhibition and anti-metastatic activity (PMID: 21285983, PMID: 32274726). |
| DrugClasses | |
| CAS Registry Number | 1144617-49-1 |
| NCIT ID | C95202 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cyclophosphamide + Nivolumab + PG545 | Cyclophosphamide Nivolumab PG545 | 0 | 1 |
| Gemcitabine + PG545 | Gemcitabine PG545 | 0 | 0 |
| Nivolumab + PG545 | Nivolumab PG545 | 0 | 1 |
| PG545 | PG545 | 0 | 0 |
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