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Drug Name | Derazantinib |
Trade Name | |
Synonyms | ARQ 087 |
Drug Descriptions |
Derazantinib (ARQ 087) is an ATP-competitive multi-kinase inhibitor with activity against Fgfr 1/2, FGFR fusions, Arg, Lck, and Kit, which prevents cell proliferation and angiogenesis (PMID: 27627808). |
DrugClasses | FGFR1 Inhibitor 28 FGFR2 Inhibitor 23 KIT Inhibitor 57 LCK Inhibitor 6 |
CAS Registry Number | 1234356-69-4 |
NCIT ID | C104267 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Derazantinib | Atezolizumab Derazantinib | 2 | 3 |
Derazantinib | Derazantinib | 19 | 4 |
Derazantinib + Paclitaxel + Ramucirumab | Derazantinib Paclitaxel Ramucirumab | 0 | 1 |