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Drug Name | AG-14361 |
Trade Name | |
Synonyms | AG14361|AG 14361 |
Drug Descriptions |
AG-14361 inhibits PARP-1, resulting in decreased survival of DNA damage repair-deficient tumor cells and increased sensitivity to chemotherapeutics and radiation (PMID: 14709739, PMID: 14871963). |
DrugClasses | PARP-1 Inhibitor 10 |
CAS Registry Number | 328543-09-5 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AG-14361 | AG-14361 | 0 | 0 |
AG-14361 + Camptothecin | AG-14361 Camptothecin | 0 | 0 |
AG-14361 + Topotecan | AG-14361 Topotecan | 0 | 0 |