AG-14361
Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | AG-14361 |
| Trade Name | |
| Synonyms | AG14361|AG 14361 |
| Drug Descriptions |
AG-14361 inhibits PARP-1, resulting in decreased survival of DNA damage repair-deficient tumor cells and increased sensitivity to chemotherapeutics and radiation (PMID: 14709739, PMID: 14871963). |
| DrugClasses | PARP-1 Inhibitor 13 |
| CAS Registry Number | 328543-09-5 |
| NCIT ID | NA |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AG-14361 | AG-14361 | 0 | 0 |
| AG-14361 + Camptothecin | AG-14361 Camptothecin | 0 | 0 |
| AG-14361 + Topotecan | AG-14361 Topotecan | 0 | 0 |
CKB BOOST