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Drug Name IDH305
Trade Name
Synonyms IDH 305|IDH-305
Drug Descriptions

IDH305 specifically targets IDH1 with mutations at amino acid R132, which results in decreased 2HG production and potentially leads to increased differentiation and decreased proliferation of IDH R132-mutant cancer cells (PMID: 29057061).

DrugClasses IDH1 Inhibitor 8
CAS Registry Number NA
NCIT ID C121457

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Therapy Name Drugs Efficacy Evidence Clinical Trials
IDH305 IDH305 3 2


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