IDH305
Drug Detail
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| Drug Name | IDH305 |
| Trade Name | |
| Synonyms | IDH 305|IDH-305 |
| Drug Descriptions |
IDH305 specifically targets IDH1 with mutations at amino acid R132, which results in decreased 2HG production and potentially leads to increased differentiation and decreased proliferation of IDH R132-mutant cancer cells (PMID: 29057061). |
| DrugClasses | IDH1 Inhibitor 8 |
| CAS Registry Number | NA |
| NCIT ID | C121457 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| IDH305 | IDH305 | 3 | 2 |
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