Z-endoxifen HCl
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| Drug Name | Z-endoxifen HCl |
| Trade Name | |
| Synonyms | Endoxifen Hydrochloride |
| Drug Descriptions |
Z-endoxifen HCl is the active metabolite of tamoxifen, which competitively inhibits estradiol binding to estrogen receptors (ER), thereby inhibiting growth of ER-positive tumors (PMID: 26232141). |
| DrugClasses | Hormone - Anti-estrogens 31 |
| CAS Registry Number | 1032008-74-4 |
| NCIT ID | C95713 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abemaciclib + Z-endoxifen HCl | Abemaciclib Z-endoxifen HCl | 0 | 1 |
| Goserelin + Z-endoxifen HCl | Goserelin Z-endoxifen HCl | 0 | 1 |
| Z-endoxifen HCl | Z-endoxifen HCl | 0 | 4 |
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