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Drug Name | Z-endoxifen HCl |
Trade Name | |
Synonyms | Endoxifen Hydrochloride |
Drug Descriptions |
Z-endoxifen HCl is the active metabolite of tamoxifen, which competitively inhibits estradiol binding to estrogen receptors (ER), thereby inhibiting growth of ER-positive tumors (PMID: 26232141). |
DrugClasses | Hormone - Anti-estrogens 29 |
CAS Registry Number | 1032008-74-4 |
NCIT ID | C95713 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Goserelin + Z-endoxifen HCl | Goserelin Z-endoxifen HCl | 0 | 1 |
Z-endoxifen HCl | Z-endoxifen HCl | 0 | 3 |