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Drug Name | MEDI0680 |
Trade Name | |
Synonyms | AMP-514|AMP514|MEDI-0680 |
Drug Descriptions |
MEDI0680 (AMP-514) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 31439037). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
CAS Registry Number | NA |
NCIT ID | C113332 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Durvalumab + MEDI0680 | Durvalumab MEDI0680 | 0 | 1 |
MEDI0680 | MEDI0680 | 0 | 1 |