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| Drug Name | MEDI0680 |
| Trade Name | |
| Synonyms | AMP-514|AMP514|MEDI-0680 |
| Drug Descriptions |
MEDI0680 (AMP-514) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 31439037). |
| DrugClasses | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 |
| CAS Registry Number | NA |
| NCIT ID | C113332 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Durvalumab + MEDI0680 | Durvalumab MEDI0680 | 0 | 1 |
| MEDI0680 | MEDI0680 | 0 | 1 |