Idetrexed
Drug Detail
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| Drug Name | Idetrexed |
| Trade Name | |
| Synonyms | ONX-0801|ONX0801|ONX 0801|BGC 945|BGC945|BGC-945 |
| Drug Descriptions |
Idetrexed (BGC-945) is a thymidylate synthase inhibitor that binds to Folr1 and is internalized via endocytosis, leading to decreased growth of Folr1-expressing cells (PMID: 16357184, PMID: 23710599). |
| DrugClasses | FOLR1-targeted Therapy 24 |
| CAS Registry Number | 501332-69-0 |
| NCIT ID | C120550 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Idetrexed | Idetrexed | 0 | 0 |
| Idetrexed + Olaparib | Idetrexed Olaparib | 0 | 1 |
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