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Drug Name | MK8033 |
Trade Name | |
Synonyms | MK-8033|HQP8361|HQP 8361|HQP-8361|MK 8033 |
Drug Descriptions |
MK8033 is an inhibitor of MET and MST1R (RON) that suppresses mTOR signaling, potentially resulting in reduced survival and colony formation, increased apoptosis, and inhibition of tumor growth (PMID: 23792360, PMID: 33163272). |
DrugClasses | MET Inhibitor 59 RON Inhibitor 11 |
CAS Registry Number | 1196681-38-5 |
NCIT ID | C116866 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
MK8033 | MK8033 | 0 | 0 |
MK8033 + Osimertinib | MK8033 Osimertinib | 0 | 0 |