Zt/g4-DM1
Drug Detail
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| Drug Name | Zt/g4-DM1 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
Zt/g4-DM1 is an antibody-drug conjugate that consists of an anti-MSTR1 (RON) antibody linked to the microtubule-inhibiting drug DM1, which resulting in endocytosis of MSTR1 (RON) and DM1, leading to increased tumor cell death and decreased growth of RON-expressing tumors (PMID: 25294907, PMID: 27102688). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Zt/g4-DM1 | Zt/g4-DM1 | 0 | 0 |
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