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Drug Name | Andecaliximab |
Trade Name | |
Synonyms | GS-5745 |
Drug Descriptions |
Andecaliximab (GS-5745) is a monoclonal antibody that binds to and inhibits matrix metalloproteinase 9 (MMP-9), which may lead to inhibition of matrix degradation and tumor metastasis (PMID: 25961845, PMID: 29691300). |
DrugClasses | |
CAS Registry Number | 1518996-49-0 |
NCIT ID | C105803 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Andecaliximab | Andecaliximab | 0 | 2 |
Andecaliximab + Bevacizumab | Andecaliximab Bevacizumab | 0 | 1 |
Andecaliximab + Fluorouracil + Leucovorin + Oxaliplatin | Andecaliximab Fluorouracil Leucovorin Oxaliplatin | 0 | 0 |
Andecaliximab + Nivolumab | Andecaliximab Nivolumab | 0 | 1 |